drugs / psychostimulants / non-psychostimulants authorized
Non-psychostimulants authorized for the treatment of ADHD
Caution
Intuniv XR:
Sedation is an undesirable effect which has been frequently reported during clinical studies.
Syncope and decreases in heart rate and blood pressure may be dose-related.
Blood pressure and heart rate may be increased when treatment is discontinued.
The effectiveness of Intuniv XR for long-term treatment, ie more than 9 weeks, has not been rigorously evaluated in controlled trials. Therefore, physicians who choose
using Intuniv XR for an extended period of time should periodically re-evaluate the long-term usefulness of this medication in each individual.
Straterra:
Possible behavioral and emotional effects that may lead to self-harm.
In the presence of jaundice or biological signs of liver damage, stop treatment and do not resume it.
Effects on growth and development should be monitored.
There have been reports of sudden death in children and adolescents with heart defects taking Strattera at usual doses.
Risks of suicidal behavior and thoughts in children have been reported.
Directions
Attention deficit disorder with or without hyperactivity (ADHD)
Contraindications
Intuniv XR:
Heart problem (a very low heart rate or a heart rhythm disorder)
Fainting in the past or current
Low blood pressure
Liver disease or kidney disease
Any other disease
Straterra:
Angle-Closure Glaucoma
Monoamine oxidase inhibitor (MAOI)
Product allergy
Pheochromocytoma (tumor condition11 sometimes malignant): possibility of high blood pressure and tachyarrhythmia
Heart disease
Moderate to severe hypotension
Advanced arteriosclerosis
Uncontrolled hyperthyroidism
Drugs interactions
Intuniv XR:
Ketoconazole antifungal used to treat fungal infections of the mouth (thrush), esophagus, reproductive tract (yeast infection) and other areas
Valproic Acid (Depakene)
Drugs that slow heart rate
Drugs that prolong the QT interval (electrical duration of heart contraction)
Straterra:
Monoamine oxidase inhibitors (MAOIs)
Desipramine (tricyclic antidepressant)
Antihypertensives and pressor agents
Side effects
They depend on the dosage and duration of treatment, the metabolism of the individual and the context in which he lives.
Frequent
Intuniv SR
Headache
Dizziness
Nausea
stomach pain
Drowsiness
Fatigue
Difficulty sleeping
Low blood pressure
strattera
In children over 6 years old and adolescents:
stomach troubles
Decreased appetite
Nausea or vomiting
Dizziness
Fatigue
Constipation
Hypotension
In adults:
Constipation
Dry mouth
Nausea
Decreased appetite
Dizziness
Difficulty sleeping
Sexual side effects
Difficulty urinating
Rapid or irregular heartbeats
Fatigue
Infrequent or rare
Intuniv SR
Fainting
Seizures
Allergic reaction to the product
strattera
Swelling or hives
Prolonged and painful erection without sexual arousal (priapism)
suicidal behavior
New psychotic or manic symptoms
Therapeutic effects
Helps increase attention span (including the ability to follow directions and complete a task) and reduce impulsivity and hyperactivity.
Monitoring and medical supervision
Intuniv SR
Before treatment :
> Warn the doctor in case of:
cardiac problem (a very low frequency heart or a heart rhythm disorder)
fainting in the past or current
low blood pressure
liver disease
kidney disease
any other disease
> Tell the doctor about all medications, vitamins, products used in alternative medicine and any plant-based product
that you take.
During treatment :
> Measure blood pressure and heart rate at the start of treatment.
> Check growth and weight regularly.
> Avoid dehydration or exposure to excessive heat.
> Measure blood pressure and heart rate at the start of treatment, after dose adjustments at regular intervals.
After treatment :
Measure blood pressure and heart rate after discontinuation of treatment.
Straterra
Before treatment :
> Warn the doctor in case of:
Structural heart abnormalities
Congenital or acquired long QT syndrome
Fainting in the past or current
mental health problem
Seizures (convulsions, epilepsy)
Brain blood vessel disorders
Family history of sudden death or death related to heart problems
Intense exercises
Taking other ADHD medications
liver disease
Hypertension
Low blood pressure
> Measure heart rate and blood pressure.
> Tell the doctor about all medicines, vitamins, products used in alternative medicine and any product herbal medicine that you take.
During treatment :
> Measure blood pressure and heart rate at the start of treatment.
> Development and growth monitoring.
> Daily observation by families and caregivers.
> Consult the doctor immediately if the following hepatic signs are present:
Dark urine
Yellow skin and eyes
Pain in the right quadrant of the abdomen
Itching
Flu-like symptoms
> Consult the doctor immediately if there is aggravation or the appearance of new emotional or behavioral problems.
After treatment :
Measure blood pressure and heart rate after discontinuation of treatment.
Withdrawal symptoms
Psychotropic drugs act in the brain just as they do in the rest of the body; and as we have seen, each person reacts differently. It's the same with weaning; the person's metabolism, the type of drug, the dose as well as the duration of the intake and its half-life, explain that the withdrawal effects are varied. We have listed the potential and main withdrawal symptoms of each class of psychotropic drugs. This list is incomplete, as not all withdrawal effects are listed; moreover, knowledge is rapidly evolving in this field. A person may have no withdrawal symptoms or experience one, a few, or even many. The medication reduction journey is specific to each person, just as each process is unique. For example, a person can take the same medicine twice at the same dose and the effects will be different. Gradual reduction, like removing 10 % of dose per week/month, reduces the frequency or intensity of withdrawal symptoms and the incidence of rapid relapses. It is very important to undertake this process with the collaboration of your doctor. The pharmacist also plays a key role and can provide guidance to monitor withdrawal effects for each drug. Most people who will have withdrawal symptoms will tolerate them without problems for the short duration of these symptoms.
Common and frequent withdrawal symptoms for all classes: anxiety, nervousness, restlessness, sleep problems, greater need to rest, sleep, irritability, fatigue.