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Voici les recherches que l'on juge les plus pertinentes au sujet du sevrage en santé mentale

Anon. 2020. « Duration and Severity of Antidepressant Withdrawal Effects ». Drug and Therapeutics Bulletin 58(1):5. doi: 10.1136/dtb.2019.000084.

Anon. s. d. « Discontinuing Psychotropic Medication: Therapeutic Advances in Psychopharmacology: SAGE Journals ». Consulté 20 septembre 2021a (

Anon. s. d. « Service-user efforts to maintain their wellbeing during and after successful withdrawal from antipsychotic medication - Miriam Larsen-Barr, Fred Seymour, 2021 ». Consulté 8 février 2022b

Balon, Richard, Edward K. Silberman, Vladan Starcevic, Fiammetta Cosci, Rafael C. Freire, Antonio E. Nardi, Karl Rickels, et Richard Shader. 2019. « Benzodiazepines, Antidepressants and Addiction: A Plea for Conceptual Rigor and Consistency ». Journal of Psychopharmacology 33(11):1467‑70. doi: 10.1177/0269881119878171

Belaise, Carlotta, Alessia Gatti, Virginie-Anne Chouinard, et Guy Chouinard. 2014. « Persistent Postwithdrawal Disorders Induced by Paroxetine, a Selective Serotonin Reuptake Inhibitor, and Treated with Specific Cognitive Behavioral Therapy ». Psychotherapy and Psychosomatics 83(4):247‑48. doi: 10.1159/000362317

Bergeron-Gaudin, Jean-Vincent. 2019. « Le transfert de l'innovation sociale et la Gestion autonome de la médication en santé mentale : les logiques alternatives du milieu communautaire à l'épreuve du pouvoir bio-médical ». Cahiers du CRISES.

Blaska, B. 1990. « The Myriad Medication Mistakes in Psychiatry: A Consumer’s View ». Hospital & Community Psychiatry 41(9):993‑98. doi: 10.1176/ps.41.9.993.

Brandt, Lasse, Tom Bschor, Jonathan Henssler, Martin Müller, Alkomiet Hasan, Andreas Heinz, et Stefan Gutwinski. 2020. « Antipsychotic Withdrawal Symptoms: A Systematic Review and Meta-Analysis ». Frontiers in Psychiatry 11. doi: 10.3389/fpsyt.2020.569912.

Brown, Marion, et Stevie Lewis. 2021. « JCPCP v20 i04 Brown&Lewis ».

Chouinard, Guy, et Virginie-Anne Chouinard. 2015. « New Classification of Selective Serotonin Reuptake Inhibitor Withdrawal ». Psychotherapy and Psychosomatics 84(2):63‑71. doi: 10.1159/000371865.

Cooper, Ruth E., Éanna Hanratty, Nicola Morant, et Joanna Moncrieff. 2019. « Mental Health Professionals’ Views and Experiences of Antipsychotic Reduction and Discontinuation ». PloS One 14(6):e0218711. doi: 10.1371/journal.pone.0218711.

Cooper, Ruth E., John P. Mason, Tim Calton, John Richardson, et Joanna Moncrieff. 2021. « Opinion Piece: The case for establishing a minimal medication alternative for psychosis and schizophrenia ». Psychosis 0(0):1‑10. doi: 10.1080/17522439.2021.1930119.

Correll, Christoph U., Jose M. Rubio, et John M. Kane. 2018. « What Is the Risk-Benefit Ratio of Long-Term Antipsychotic Treatment in People with Schizophrenia? » World Psychiatry 17(2):149‑60. doi:

Cosci, Fiammetta, et Guy Chouinard. 2020. « Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications ». Psychotherapy and Psychosomatics 89(5):283‑306. doi: 10.1159/000506868.

Crowe, M., Inder, M., & McCall, C. (2022). Experience of antidepressant use and discontinuation: A qualitative synthesis of the evidence. Journal of Psychiatric and Mental Health Nursing, 00, 1– 14.

Davies, James, et John Read. 2019. « A Systematic Review into the Incidence, Severity and Duration of Antidepressant Withdrawal Effects: Are Guidelines Evidence-Based? » Addictive Behaviors 97:111‑21. doi: 10.1016/j.addbeh.2018.08.027.

Ellen, Van Leeuwen, Sibyl Anthierens, Mieke L. van Driel, An De Sutter, Evelien van den Branden, et Thierry Christiaens. 2021. « ‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants ». Scandinavian Journal of Primary Health Care 39(4):533‑42. doi: 10.1080/02813432.2021.2006487.

Fava, Giovanni A. 2020. « May Antidepressant Drugs Worsen the Conditions They Are Supposed to Treat? The Clinical Foundations of the Oppositional Model of Tolerance ». Therapeutic Advances in Psychopharmacology 10:2045125320970325. doi: 10.1177/2045125320970325.

Fava, Giovanni A., Giada Benasi, Marcella Lucente, Emanuela Offidani, Fiammetta Cosci, et Jenny Guidi. 2018. « Withdrawal Symptoms after Serotonin-Noradrenaline Reuptake Inhibitor Discontinuation: Systematic Review ». Psychotherapy and Psychosomatics 87(4):195‑203. doi: 10.1159/000491524.

Fava, Giovanni A., et Fiammetta Cosci. 2019. « Understanding and Managing Withdrawal Syndromes After Discontinuation of Antidepressant Drugs ». The Journal of Clinical Psychiatry 80(6). doi: 10.4088/JCP.19com12794.

Framer, Adele. 2021. « What I Have Learnt from Helping Thousands of People Taper off Antidepressants and Other Psychotropic Medications ». Therapeutic Advances in Psychopharmacology 11:2045125321991274. doi: 10.1177/2045125321991274.

Goff, Donald C., Peter Falkai, W. Wolfgang Fleischhacker, Ragy R. Girgis, Rene M. Kahn, Hiroyuki Uchida, Jingping Zhao, et Jeffrey A. Lieberman. 2017. « The Long-Term Effects of Antipsychotic Medication on Clinical Course in Schizophrenia ». American Journal of Psychiatry 174(9):840‑49. doi: 10.1176/appi.ajp.2017.16091016.

Groot, Peter C., et Jim van Os. 2020. « How User Knowledge of Psychotropic Drug Withdrawal Resulted in the Development of Person-Specific Tapering Medication ». Therapeutic Advances in Psychopharmacology 10:2045125320932452. doi: 10.1177/2045125320932452.

Haddad, Peter. 1998. « The SSRI Discontinuation Syndrome ». Journal of Psychopharmacology 12(3):305‑13. doi: 10.1177/026988119801200311.

Harris, Rachael, et Jon Crossley. s. d. « A Systematic Review and Meta-Synthesis Exploring Client Experience of Reflecting Teams in Clinical Practice ». Journal of Family Therapy n/a(n/a). doi:

Hengartner, Michael P. 2017. « Methodological Flaws, Conflicts of Interest, and Scientific Fallacies: Implications for the Evaluation of Antidepressants’ Efficacy and Harm ». Frontiers in Psychiatry 8. doi: 10.3389/fpsyt.2017.00275.

Hengartner, Michael P., James Davies, et John Read. 2020. « Antidepressant Withdrawal – the Tide Is Finally Turning ». Epidemiology and Psychiatric Sciences 29. doi: 10.1017/S2045796019000465.

Hengartner, Michael P., Lukas Schulthess, Anders Sorensen, et Adele Framer. 2020. « Protracted Withdrawal Syndrome after Stopping Antidepressants: A Descriptive Quantitative Analysis of Consumer Narratives from a Large Internet Forum ». Therapeutic Advances in Psychopharmacology 10:2045125320980573. doi: 10.1177/2045125320980573.

Højlund, Mikkel, Adam F. Kemp, Peter M. Haddad, Joanna C. Neill, et Christoph U. Correll. 2021. « Standard versus Reduced Dose of Antipsychotics for Relapse Prevention in Multi-Episode Schizophrenia: A Systematic Review and Meta-Analysis of Randomised Controlled Trials ». The Lancet Psychiatry 8(6):471‑86. doi: 10.1016/S2215-0366(21)00078-X.

Horowitz, Mark Abie, Sameer Jauhar, Sridhar Natesan, Robin M. Murray, et David Taylor. 2021a. « A Method for Tapering Antipsychotic Treatment That May Minimize the Risk of Relapse ». Schizophrenia Bulletin. doi: 10.1093/schbul/sbab017.

Horowitz, Mark Abie, Sameer Jauhar, Sridhar Natesan, Robin M. Murray, et David Taylor. 2021b. « A Method for Tapering Antipsychotic Treatment That May Minimize the Risk of Relapse ». Schizophrenia Bulletin 47(4):1116‑29. doi: 10.1093/schbul/sbab017.

Horowitz, Mark Abie, Robin M. Murray, et David Taylor. 2021a. « Tapering Antipsychotic Treatment ». JAMA Psychiatry 78(2):125‑26. doi: 10.1001/jamapsychiatry.2020.2166.

Horowitz, Mark Abie, Robin M. Murray, et David Taylor. 2021b. « Withdrawal-Associated Relapse Is a Potential Source of Bias ». The Lancet Psychiatry 8(9):747‑48. doi: 10.1016/S2215-0366(21)00250-9.

Horowitz, Mark Abie, et David Taylor. 2019. « Tapering of SSRI Treatment to Mitigate Withdrawal Symptoms ». The Lancet Psychiatry 6(6):538‑46. doi: 10.1016/S2215-0366(19)30032-X.

Horowitz, Mark Abie, et David Taylor. 2022. « How to Reduce and Stop Psychiatric Medication ». European Neuropsychopharmacology 55:4‑7. doi: 10.1016/j.euroneuro.2021.10.001.

Horowitz, Mark, et Michael Wilcock. 2022. « Newer Generation Antidepressants and Withdrawal Effects: Reconsidering the Role of Antidepressants and Helping Patients to Stop ». Drug and Therapeutics Bulletin 60(1):7‑12. doi: 10.1136/dtb.2020.000080.

Huff, Christy. 2021. « Response to “Acute and Persistent Withdrawal Syndromes Following Discontinuation of Psychotropic Medications” by Cosci et al. (2020) ». Psychotherapy and Psychosomatics 90(3):207‑8. doi: 10.1159/000514045.

Iacobucci, Gareth. 2019. « NICE Updates Antidepressant Guidelines to Reflect Severity and Length of Withdrawal Symptoms ». BMJ 367:l6103. doi: 10.1136/bmj.l6103.

Jauhar, Sameer, Joseph Hayes, Guy M. Goodwin, David S. Baldwin, Philip J. Cowen, et David J. Nutt. 2019. « Antidepressants, Withdrawal, and Addiction; Where Are We Now? » Journal of Psychopharmacology (Oxford, England) 33(6):655‑59. doi: 10.1177/0269881119845799.

Jha, Manish K., A. John Rush, et Madhukar H. Trivedi. 2018. « When Discontinuing SSRI Antidepressants Is a Challenge: Management Tips ». American Journal of Psychiatry 175(12):1176‑84. doi: 10.1176/appi.ajp.2018.18060692.

Karter, Justin M. 2020. « Conversations with Clients about Antidepressant Withdrawal and Discontinuation ». Therapeutic Advances in Psychopharmacology 10:2045125320922738. doi: 10.1177/2045125320922738.

Lehmann, Peter. 2018. Psychotropes, Réussir son Sevrage – Se sevrer avec succès des neuroleptiques, antidéprésseurs, thymorégulateurs, psychostimulants et tranquilisants.

Lerner, Alicja, et Michael Klein. 2019. « Dependence, withdrawal and rebound of CNS drugs: an update and regulatory considerations for new drugs development ». Brain Communications 1(1). doi: 10.1093/braincomms/fcz025.

Lincoln, Tania M., Daniel Sommer, Marie Könemund, et Björn Schlier. 2021. « A Rating Scale to Inform Successful Discontinuation of Antipsychotics and Antidepressants ». Psychiatry Research 298:113768. doi: 10.1016/j.psychres.2021.113768.

Lindblad, Anna, Gert Helgesson, et Manne Sjöstrand. 2019. « Towards a Palliative Care Approach in Psychiatry: Do We Need a New Definition? » Journal of Medical Ethics 45(1):26‑30. doi: 10.1136/medethics-2018-104944.

McCabe, Joanne, Mike Wilcock, Kate Atkinson, Richard Laugharne, et Rohit Shankar. 2020. « General Practitioners’ and Psychiatrists’ Attitudes towards Antidepressant Withdrawal ». BJPsych Open 6(4):e64. doi: 10.1192/bjo.2020.48.

Mendes, Aysha. 2019. « Depression, Antidepressants and Withdrawal in the Community ». British Journal of Community Nursing 24(10):508‑9. doi: 10.12968/bjcn.2019.24.10.508.

Moncrieff, J. 2018. « Research on a ‘Drug-Centred’ Approach to Psychiatric Drug Treatment: Assessing the Impact of Mental and Behavioural Alterations Produced by Psychiatric Drugs ». Epidemiology and Psychiatric Sciences 27(2):133‑40. doi: 10.1017/S2045796017000555.

Moncrieff, Joanna. 2018. « Against the stream: Antidepressants are not antidepressants – an alternative approach to drug action and implications for the use of antidepressants ». BJPsych Bulletin 42(1):42‑44. doi: 10.1192/bjb.2017.11.

Moncrieff, Joanna, Swapnil Gupta, et Mark Abie Horowitz. 2020. « Barriers to Stopping Neuroleptic (Antipsychotic) Treatment in People with Schizophrenia, Psychosis or Bipolar Disorder ». Therapeutic Advances in Psychopharmacology 10:2045125320937910. doi: 10.1177/2045125320937910.

MS, Ashley Bobak. 2021. « Cochrane Review Calls for More Research on Antidepressant Withdrawal ». Mad In America. Consulté 10 mai 2021 (

Papp A, Onton JA. Triggers and characteristics of brain zaps according to the findings of an internet questionnaire. Prim Care Companion CNS Disord. 2022;24(1):21m02972.

Pies, Ronald, W., et David Osser N. s. d. « Sorting Out the Antidepressant “Withdrawal” Controversy ». Psychiatric Times. Consulté 24 mars 2021 (

Qureshi, Mutahira M., et Allan H. Young. 2021. « Hamlet’s Augury: How to Manage Discontinuation of Mood Stabilizers in Bipolar Disorder: » Therapeutic Advances in Psychopharmacology. doi: 10.1177/20451253211000612.

Read, John." The experiences of 585 people when they tried to withdraw from antipsychotic drugs",
Addictive Behaviors Reports, Volume 15, 2022, 100421, ISSN 2352-8532,

Robinson, Julia. s. d. « Prescribers Should Warn Patients about Dependence before Starting Them on High-Risk Drugs, Says NICE ». The Pharmaceutical Journal. Consulté 26 octobre 2021 (

Stockmann, Tom. 2019. « What it was like to stop an antidepressant ». Therapeutic Advances in Psychopharmacology 9:2045125319884834. doi: 10.1177/2045125319884834.

Stockmann, Tom, Dolapo Odegbaro, Sami Timimi, et Joanna Moncrieff. 2018. « SSRI and SNRI Withdrawal Symptoms Reported on an Internet Forum ». The International Journal of Risk & Safety in Medicine 29(3‑4):175‑80. doi: 10.3233/JRS-180018.

Strand, Mattias, Manne Sjöstrand, et Anna Lindblad. 2020. « A palliative care approach in psychiatry: clinical implications ». BMC Medical Ethics 21(1):29. doi: 10.1186/s12910-020-00472-8.

Tomlinson, Anneka, Katharine Boaden, et Andrea Cipriani. 2019. « Withdrawal, Dependence and Adverse Events of Antidepressants: Lessons from Patients and Data ». Evidence-Based Mental Health 22(4):137‑38. doi: 10.1136/ebmental-2019-300121.

Torjesen, Ingrid. 2021. « Antidepressants: Evidence on Safe Discontinuation Is Lacking, Concludes Cochrane Review ». BMJ 373:n1065. doi: 10.1136/bmj.n1065.

Van Leeuwen, Ellen, Mirko Petrovic, Mieke L. van Driel, An Im De Sutter, Robert Vander Stichele, Tom Declercq, et Thierry Christiaens. 2018. « Withdrawal versus Continuation of Long-Term Antipsychotic Drug Use for Behavioural and Psychological Symptoms in Older People with Dementia ». The Cochrane Database of Systematic Reviews 3:CD007726. doi: 10.1002/14651858.CD007726.pub3.

White, Edward, John Read, et Sherry Julo. 2021. « The Role of Facebook Groups in the Management and Raising of Awareness of Antidepressant Withdrawal: Is Social Media Filling the Void Left by Health Services? » Therapeutic Advances in Psychopharmacology 11:2045125320981174. doi: 10.1177/2045125320981174.

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